The last male representative of the human species and his road companions are halfway on their journey to San Francisco and Dr Mann's crucial discoveries. But before they continue, they must find antibiotics for the only other male survivor of the planet: Esperluette, Yorick's monkey. For the latter, this means that he will remain cloistered at the bottom of Colorado with Agent 711, a former colleague of the 355 now retired. But Yorick will live much more than a quiet country weekend. What awaits him in the little cabin of 711 will be more trying than all the dangers he has faced until then and could sign the death stop of the Last Man. Stop-Encore collects episodes 18 to 23 of the popular series created by Brian K.Vaughan and Pia Guerra, and presents new challenges to the complex characters of this haletante saga of anticipation.