Reed Richards seeks to solve humanity’s greatest problems while maintaining the fragile balance of his own family. His research brings him into contact with the Council of Reeds, a group made up of alternate versions of himself who sacrificed their personal lives in the name of progress. Meanwhile, the Fantastic Four face new threats involving the Inhumans, the Atlanteans, the Negative Zone, and several alien civilizations. As the crises escalate, Reed, Sue, Johnny, and Ben must confront choices capable of transforming their family, their team, and the future of Earth itself.