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On one night in 1986, an ethical decision will lead Dr.Kenzo TENMA to save the life of a child at the expense of the dumairedelaville.How could he know that his act would have such consequences?For the child whom he saved, grew up, and seems to be called "Monster".
1995, Dusseldorf, Germany. Dr. Tenma now knows that his irreproachable attitude as a doctor has had a terrible consequence. "Johann" grew up and became a diabolical murderer nicknamed "Monster". Thus begins his desperate race after "Johann". The road is long and not safe !!
Tenma goes to Berlin to try to elucidate the mystery of Johann's birth. The terrible truth he finds there tells him that horrible experiments would have been carried out in East Germany. But who is this Johann?! And what is "the orphanage 511"?!
In order to kill his brother Johann, Nina infiltrated a very unhealthy organisation in Berlin. As for Tenma, he is in the same city in the heart of the Turkish quarter. Will chance allow their roads to cross again!?
Hoping to decipher the enigmatic message left by Johann, Tenma visits Professor Gillen, one of his former university comrades and specialist in criminal psychology. But, he only manages to reinforce the doubts that weigh on him and he finds himself at the foot of the wall...
Driven by love and hatred, Eva persists in wanting to find her ex-fiance, Tenma. One day, in her life of debauchery, she meets a man... Who is he? And where is Tenma?
Richard Brown had completely descended into alcoholism after having to leave the police force due to a serious mistake during a case. And finally, he was also abandoned by his family. Having regained his senses, Richard decides to start anew by becoming a detective.
Temma obtained a high-precision rifle and followed all Johann's actions very closely. One day, he learned that Johann had to attend the presentation of Schuwald's collection of works at the Munich library. He then made the decision to shoot Johann at the ceremony.
Tenma has decided to assassinate Johann and stands ready, hidden in the university library. How will Johann react when he realizes that Tenma has a rifle pointed at him? Does Tenma's life as a fugitive come to an end? The tension of history is at its peak!!
Tenma infiltrates the Czech Republic in search of Johann's mother. He is spotted by the border police but manages to escape with the help of Grimmer, a freelance journalist. The two men begin to exchange the reasons that brought them to this country. In reality, Grimmer is very interested in the 511 Kinderheim that once existed in East Germany. The story now continues in Prague!
An apartment in an old building in the lower quarters of Prague with a sign adorned with three frogs. A woman lived there with her two children, twins, about ten years ago. This is what Temma learns from the neighbors. They also tell him about the Czechoslovak secret police and a strange fire. Could the twins be Johann and Anna? Meanwhile, Suk, a young Prague police inspector, falls for a pretty girl he met in a bar. Her name is Anna! When Tenma and Suk meet, a new tragedy is brewing around them!
The director of the Prague orphanage is said to have been killed by a "beautiful blonde girl". Tenma starts in his footsteps in the company of Grimmer, wanted for the same murder, but their efforts do not end. Meanwhile, Milosh, one of the boys of the orphanage who knows that Grimmer is innocent, is being dragged into an unpopulated area of a border town!!! Tenma approaches the truth, but he still has no concrete evidence. The police, on the other hand, has a man who is... !!!
After being arrested in Prague, Tenma is transferred to Düsseldorf. He then discovers that one of his lawyers is Robert, a fervent waiter of Johann !!! The latter confesses to him his intention to kill Eva. In order to save her, Tenma must escape. To this end, he makes a false confession acknowledging that he is the perpetrator of the crimes for which he is suspected...
In an effort to save Eva, Tenma escapes from prison, and with the only clue being a note left by his lawyer, Master Verdeman, he heads to the rose villa. Meanwhile, Nina, who is trying to bring back memories of her childhood, has also arrived at the villa. She enters the house and crosses the doorway at the end of the corridor. She then has a flash vision of that horrible scene.
Eva knew Johann... That is why she was kidnapped and taken to Frankfurt by an extreme right-wing organization that wanted to get in touch with him. Martin, the bodyguard who had promised to protect Eva, received the order to "finish his job"...! At the same time, Tenma followed Eva to Frankfurt with the firm intention of ending things with Johann, but...
This time the end is near for Johann. After following him, Tenma ended up finding a serious track concerning his intentions. Meanwhile, Nina meets Peter Capek, head of a branch of the far right and recaptured from "the rose villa". Capek is about to reveal the terrifying truth that lies behind the birth of the twins.
Nina, who has recovered her entire memory, is face-to-face with Johann!! She begins to speak and reveals the secret of the "villa of roses" and the atrocious truth about the birth of the "Monster"!! At the same time, Runge and Grimmer arrive in a small town in the middle of the mountains. Are they looking for someone who lives there?!
Ruhenheim: "a quiet house." An ordinary small town, like any other, has fallen into a murderous madness! What is the "perfect suicide" that Johann spoke of? Will Runge and Grimmer be able to stop the massacre? Tenma and Nina are now together facing Johann. And this time, the secret of the twins' birth will be revealed! A surprising end to this series of twists and turns.