In 1938, Joseph Joestar, grandson of Jonathan Joestar, discovers that the threat of the Stone Mask has not disappeared. When ancient beings known as the Pillar Men awaken, he is drawn into a battle against enemies capable of manipulating their bodies and surpassing normal human limits. Unlike his grandfather, Joseph relies as much on intelligence, provocation, and trickery as he does on Hamon. Alongside Caesar Zeppeli and Lisa Lisa, he must sharpen his abilities to prevent the Pillar Men from obtaining a stone capable of increasing their power even further. Through travel, training, and spectacular battles, Joseph faces a threat that could endanger all of humanity.