After the rescue of Bloody Mary and her companion, Ryo's team has to solve a new case... Indeed, Saeko needs help in the investigation of the pharmaceutical group Bibirwa, which would be at the heart of a major drug trade! The company's director is Robert Steiner, a former soldier of the Latuanian army. For City Hunter, we must get rid of this enemy as soon as possible... Unfortunately, the task is more difficult than expected, because the man is not going back to anything to achieve his ends!