Thanks to City Hunter, the kidnapping of the Snake brothers failed and J. J., rid of his old demons, can finally start a new life! For his part, Sayuri finally decided to entrust his sister to Ryo... The young woman knows that Kaori's place is at the side of the man she loves. Shortly afterwards, while the team is looking for a new mission, Ryo falls nose to nose with an old knowledge as beautiful as it is dangerous: Rosemary Moon, her former partner, also known as Bloody Mary! Only, the famous cleaner doesn't seem very happy to see her again...