Will the alliance between Spider-Man and the Green Bouffon survive their first defeat and the return of the Ultimates? Tony Stark's team wants to consolidate its ranks... maybe thanks to Miss Hulk? What really has the Reed Richards of the Ultimate universe been through in the hands of the Creator? It is time for the confrontation between Wakanda and Moon Knight, as well as between the young mutants and the terrifying creature who is attacking Hisako.